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Immune Synapse & Cell Therapy Laboratory

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[NEWS]Role of subnuclear NSrp70 in immunity-studied at Gwangju Institute of Science & Technology

작성자Immune Synapse & Cell Therapy Laboratory  조회수487 Date2021-07-26
링크
Role of subnuclear NSrp70 in immunity-studied at Gwangju Institute of Science & Technology | EurekAlert! Science News

요약
In 2011, scientists from the Gwangju Institute of Science and Technology (GIST) in Korea discovered a protein called NSrp70, which is abundant in motile T cells. Located in specific regions inside the cell's nucleus called nuclear speckles, NSrp70, which is short for nuclear speckle-related protein 70, is a gene regulator. Interestingly, nuclear speckles play an important role in protein production by housing mRNA splicing regulators that cut and join pre-messenger RNA fragments to produce the final messenger RNAs based on the proteins that are produced. With this knowledge, the scientists have been speculating about the possible role NSrp70 plays in the alternative splicing involved in T cell maturation and development.

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